Neurite outgrowth stimulatory effects of culinary-medicinal mushrooms and their toxicity assessment using differentiating Neuro-2a and embryonic fibroblast BALB/3T3

Neurite outgrowth stimulatory effects of culinary - medicinal 1 mushrooms and their toxicity assessment using differentiating 2 Neuro - 2 a and embryonic fibroblast BALB / 3 T 3

Aqueous extracts of Ganoderma lucidum, Lignosus rhinocerotis, Pleurotus giganteus

31 Background 32 Mushrooms are not only regarded as gourmet cuisine but also as therapeutic agent to 33 promote cognition health. However, little toxicological information is available regarding 34 their safety. Therefore, the aim of this study was to screen selected ethno35 pharmacologically important mushrooms for stimulatory effects on neurite outgrowth and 36 to test for any cytotoxicity. 3...

Therapeutic potential of culinary-medicinal mushrooms for the management of neurodegenerative diseases: diversity, metabolite, and mechanism.

Mushrooms have long been used not only as food but also for the treatment of various ailments. Although at its infancy, accumulated evidence suggested that culinary-medicinal mushrooms may play an important role in the prevention of many age-associated neurological dysfunctions, including Alzheimer's and Parkinson's diseases. Therefore, efforts have been devoted to a search for more mushroom sp...

Neuronal Health – Can Culinary and Medicinal Mushrooms Help?

Hericium erinaceus a culinary and medicinal mushroom is a well established candidate for brain and nerve health. Ganoderma lucidum, Grifola frondosa and Sarcodon scabrosus have been reported to have neurite outgrowth and neuronal health benefits. The number of mushrooms, however, studied for neurohealth activity are few compared to the more than 2 000 species of edible and / or medicinal mushro...

Biochemical analysis of cell-derived apoE3 particles active in stimulating neurite outgrowth.

Susceptibility to the development of late-onset Alzheimer's disease is increased for individuals harboring one or more apolipoprotein E4 (apoE4) alleles. Although several isoform-specific effects of apoE have been identified, the relationship between biochemical function and risk factor assessment is unknown. Our previous studies showed that a physiologically relevant cell-derived apoE3 particl...